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Avian Influenza (Epidemiology (Important reservoir is wild birds (Ducks,…

- - - - Spreads throughout respiratory tract (1 - 3 days)
        
        necrosis of epithelial cells and defective mucocilliary transport
        
        Potential for secondary bacterial infection (e.g. Pneumonia)
    - - Shed in faeces
      - More virulent strains causes systemic disease and viraemia
- - - - 6 birds
        
        3 acute disease
        
        3 recently deceased
    - - tracheal and cloaca swabs into brain heart infusion broth + penicillin + Streptomycin
      - Blood samples collected for serum
    - - Swab tracheal and cloacal contents, brain, heeart blood
      - impression smears of internal organs (kidney, pancreas)
      - Cell culture from unpreserved brain, trachea,spleen
    - - Viral antigen
      - Viral isolation
      - PCR