Please enable JavaScript.
Coggle requires JavaScript to display documents.
NeuroRehabilitation (Functional recovery (Vicarious function: taking over…
NeuroRehabilitation
Functional recovery
- Vicarious function: taking over of the functions of the injured part by distant back up areas with the same functional capacity
- Degeneracy: performance of the same function by multiple neuronal systems
-
- Redundancy: maintenance of function of a damaged system by parts that were not injured
- Spontaneous disappearance of acute effects of traumatic or ischemic lesions e.g. chemical modifications
damaged but surviving neurons can try to re-establish at least some functional connections (through axonal & dendritic sprouting, synaptogenesis)
Dentate gyrus (component of hippocampal formation): the only region of human brain with evidence of adult neurogenesis --> flexible, replacing lost neurons, suitable environment for information acquisition, enhanced excitability & facilitated LTP expression in immature neurons
optimal when the current stage of development & maturation is most favorable to synaptogenesis & glial formation
-
-
-
What is it?
intends to enable patients & their families to live with, manage, bypass, reduce, or come to terms with cognitive deficits
Training, Education, Environmental Adaptation but more specific: Cognitive Training
can apply to any intervention, strategy, technique
Future: couple traditional interventions of rehabilitations (ie. behavioral, cognitive) with advanced neurological treatments eg. brain stimulation, transplantation of stem cells, gene therapies, BMIs
-
Young vs. Old Brain
-
Aged brain
-
-
some neurons show normal or overdeveloped dendritic architectures --> maintained capacity for learning & memory
massive numerical decrease of cortical neurons & glia in Alzheimer's dementia & neurodegenerative diseases
-
-
-
-
Negative effects? If motor compensation comes too early ---> some functions that were intact before may become impaired