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MOVEMENT (STRUCTURE OF MUSCLE FIBRES ((• They are multinucleate (fibres…

- - - - • Each myofibril is made up of contractile sarcomere
      - • The part of myofibril between one z line to another is called sarcomere
      - • Thin actin filaments are attached to Z-line at one end
      - • Thick myosin filaments are interdigitated with filaments at both end and occupy the centre of sacromere
- - - - Myosin filaments have heads which for cross bridges when they are attached to binding sites on actin filaments
      - ATP binds to the myosin heads and causes them to break the cross-bridges by detaching from the binding sites
      - ATP is hydrolysed to ADP and phosphate, causing the myosin heads to change their angle. The heads are said to be ‘cocked’ in their new position as they are storing potential energy from ATP.
      - The heads attach to binding sites on actin that are further from the centre of sarcomere than the previous sites.
      - The ADP and phosphate are released and the heads push the actin filament inwards towards the centre of the sarcomere-this is called the power stroke.