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Vitamin B6 Water soluble (Deficiency (symptoms (microcytic anaemia,…
Vitamin B6
Water soluble
Description
3 natural forms
each also occurs as phosphorylated compound
pyridoxine
pyrdoxamine
pyridoxal
principle form found in body and food
pyrdoxal 5-phosphate
Functions
involved in fatty acid metabolism
helps convert tryptophan to niacin and serotonin
coenzyme in synthesis and catabolism of amino acids
helps make red blood cells
sources
cooking and processing may destroy up to 50% in some foods
milling removes significant amounts of B6
major sources
meat
liver
organ meats
whole grain cereal
vegetables
nuts
Deficiency
certain medications interfere with
symptoms
microcytic anaemia
cheliosis
scaly dermatitis
glossitis
epileptiform convulsions
depression
confusion
deficiency more likely if
alcohol abuse
consumption of mainly processed foods
lack of nutritious food intake
Treatment
first pyridoxine injected intramuscularly
next pyridoxine given orally
rare as most food contain this vitamin
Excess
no adverse effects when excess from food sources
large oral supplementation can lead too
sensory neuropathy
dermatological lesions
premenstrual syndrome