Most commonly dispensed drug in small animal practice
• Still works against beta lactamase producing bacteria
• Predominantly for gram-positive and anaerobic bacteria but can
target Pasteurella spp. Pasteurella spp. are commonly found occurring after cat bites or in BRD, but they have poor penetration into the lungs, so not effective for BRD treatment.
• Low MIC for Streptococcus and Staphylococcus spp.
• Good distribution into most tissues, except for abscesses,
pneumonia and mastitis. Penetrates into tissues better than
• Always IM or IC (coconut oil can cause an embolism if
• Not recommended – but if accidental administration to small
hindgut fermenters, e.g. guinea pigs, will cause death as the drug accumulates in the hindgut, in larger animals, e.g. horses, the same amount of drug will not kill the animal.