Please enable JavaScript.
Coggle requires JavaScript to display documents.
1.3 Membrane Structure (Membrane proteins (Functions of membrane proteins,…
1.3 Membrane Structure
Membrane proteins
-
Type of membrane protein
-
peripheral
-
mostly are attached to surface of integral protein, this attachment is often reversible
-
phospholipid bilayer
amphipathic, both hydrophilic (phosphate group) and hydrophobic (hydrocarbon chains)
Experiments
Davson and Danielli, membrane proteins are sandwiched between phospholipid layers, supported by electron microscope
Singer and Nicolson, membrane proteins occupy variety of positions, fluid mosaic model
Gorter and Grendel extracted phospholipids from plasma membrane, area of phopholipid is twice the area of cell
Cholesterol in membranes
Cholesterol
a type of lipid, grouped under steroid
-
-
Roles of cholesterol
disrupts the regular picking of hydrocarbon tails preventing them from crystallizing and behaving as a solid
-
-
help membrane to curve into concave shape, helps in the formation of vesicles during endocytosis