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chapter 11: cardiovascular system: blood: 11-5 (WBC count (average wbc…
chapter 11: cardiovascular system: blood: 11-5
types and function of WBC's
leukocytes function to control disease. leukocytes are divided into granulocytes and agranulocytes
granulocytes
neutrophils
most abundant WBC = 54%-62%
polymorphonucleocytes
phagocytosis of foreign particles
increase in acute bacterial infections
eosinophils
1-3% of total WBC's
kills parasites and are responsible for allergic reactions
increased during parasitic infections
released histamines during allergic reaction
basophils
<1% of total WBC's
release heparin which inhibits blood clotting
release histamine, a vasodilator helpful inflammatory responses
may leave bloodstream and develop into mast cells
agranulocytes
monocytes
3-9% of total WBC's
phagocytosis
largest WBC, 12-20 microns
in blood= phagocyte; in tissues= macrophage
increased during typhoid fever, malaria, and mononucleosis
lymphocytes
25-33% of total WBC's
live for several months to years
range in size from large to small
t-cells
attack cells directly
b-cells
produce antibodies that act against specific foreign substances
increased during TB, whooping cough,viral infections, tissue rejection
diapedesis = process by which leukocytes move through the blood vessel walls to enter tissues
WBC count
average wbc count = 5000-10000
number of wbc's increases during infections
leukoctyosis =wcc>10000
leukopenia = wcc<5000
differential wcc indicates % of each particular leukocyte
leukemia= abnormal production of specific types of immature leukocytes
lymphopoiesis
colony stimulating factors
multi, gm, g,and m
myeloid stem cells
neutrophils, eosinophils, basophils, mature in bone marrow
lymphoid stem cells can also be produced in spleen,thymus, and lymph nodes
t cells mature in thymus
b cells mature in bone marrow