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DNA replication (Introduction (Structure of DNA (Two anti-parallel…
DNA replication
Introduction
DNA is found in the nucleus. The molecule is twisted into a double helix in which the strands are ant parallel. It has two sugar phosphate backbones attached to one another by complimentary bases. These bases pair in the centre of the molecule by hydrogen bonds.
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Structure of DNA
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Four polynucleotide bases (Adenine, Thymine, Cytosine, Guanine).
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Before a cell divides by mitosis or meiosis, the DNA in the nucleus is copied or replicated. Before the mechanism of DNA replication was known in full, two hypotheses were put forward.
Conservative replication:
This would involve a completely new double stranded copy of DNA being made and the original or parental DNA staying the same (being conserved).
Semi- conservative replication
This would involve separation of the DNA strands followed by replication of each strand separately to produce DNA half parental and half new. So one strand acts as a template for the new strand.
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