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Lab hemostasis (Coagulation disorder (Bleeding prolonged aPTT, PT, normal…

- - - - Mixing study corrected
        
        Factor def.
        
        FVIII def.
        
        Hemophilia A
        
        FIX def.
        
        Hemophilia B
        
        FXI def.
        
        Hemophilia C
      - Mixing study not corrected
        
        Factor inh.
        
        FVIII, FIX, FXI
    - - Mixing study not corrected
        
        Lupus anticoagulant
      - Mixing study corrected
        
        Factor def.
        
        FXII, PK, HMWK
  - - - Congenital (rare)
      - Acquired
        
        Liver disease
        
        Vit K def.
  - - - If lab from central line
        
        Repeat lab from peripheral line
  - - - Heparin contamination
      - Hyperfibrinogenemia
    - - Hypofibrinogenemia
      - Dysfibrinogenemia
      - Impaired fibrinpolymerization
      - Anti IIa
- - - - BM disease, suppression
    - - Disseminated intravascular coagulopathy (DIC)
      - Thrombotic theombocytopenic purpura (TTP)
      - Idiopathic (ITP)
      - SLE
      - Infection
        
        Viral : hepC, hepB
    - - Splenomegaly
    - - เกิด bleeding ให้แต่ RBC, plasma transfusion ลืมให้ Plt
  - - - VWF disease
      - Plt receptor เสีย
        
        Bernard-Soulier
        
        Glanzmann (Thrombasthenia)
        
        Gray
        
        Storage pool
    - - Aspirin, NSAIDs
      - Uremia
      - APDE eosinophilia in child
      - Antiplatelet antibody