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Introduction to Cardiovascular Diseases, Implants, and Bio-engineering…

- - - - attempted placement of plastic stents that thrombosed after 24 hours
      - later animal studies used both stainless steel coil and nitinol coils (1983)
  - - - Abbott will end sales of Absorb Bioresorbable sent on September 8, 2017
- - - - greater effective opening area
      - better thermodynamics
      - minimal blood thinner requirement
      - less thrombogenic
      - Materials
        
        Struts and occluders
        
        Pryrolytic carbon (graphite-reinforced plastic)
        
        Titanium coated with pyrolytic carbon
        
        Sewing Cuff
        
        Teflon
        
        polyester
        
        dacron
    - - blood flows backwards in consequence of it
- - - - Specified and controlled designed characteristics(e.g. orifice area, valve height, degree of coaptation
      - Glutraldehyde fixatiion to reduce foreign reaction .625%
      - mimic geometry and flow dynamics of natural human aortic valve
      - less stenotic compared to porcine bioprosthesis
        
        Due to pericardial design and increased orifice area