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Uremic Pruritus (Causes (2 main streams (Chronic inflammation…
Uremic Pruritus
Causes
2 main streams
Chronic inflammation
inflammatory mediators
CRP
IL2
IL6
Ferritin
Low albumin
u opium receptor overexpress
Underdialysis
Ca /P imbalance
high serum Al or Mg
biocompatibility of dialyzer/ bloodline/heparin
hypersensitive
Dry skin
HCV patient
Patient itchy
Uremic Pruritus
Other Causes
Summary
1 out of 8 causes by chronic inflammation
3 out of 8 causes due to dialysis
Prevalence
Over 40% of medium and severe(DOPPS)
