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Clostridium (Characteristics (Rods, Anaerobic, Non-Motile, Catalase +ve,…

- - - - Spores germinate in wound
        
        2.production of endotoxins
        
        3.TeNT is released in the ventral horn
        
        Blocks inhibitory mediators
        
        Tonic spasms and paralysis
  - - - Neurotoxin ingested/inhaled
        
        2.Absorbed through the GIT
        
        3.Blood stream
        
        Peripheral nerves
        
        5.ACh inhibitores
        
        6.Flaccid Paralysis
- - - - 1.Enter through ingestion
        
        Animal immune deficient
        
        bacteria proliferate in the gut
        
        produce toxins
        
        Generalised endothelial damage
- - - - 1.Ingestion of bacteria
        
        Migrate into bloodstream
        
        3.enter liver
        
        Anaerobic environment produced by migrating liver fluke
        
        bacteria germinate and produce toxins