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Patho CH 38 Diuretics (Types (Thiazide and thiazide-like (Action (Act on…

- - - - Act on distal convoluted renal tubule
      - Promote sodium, chloride, and water excretion
    - - Hypertension
      - Peripheral edema
  - - - Act on ascending loop of Henle
      - Excrete sodium, water, potassium, calcium, magnesium
  - - - Increase sodium reabsorption in the proximal tubule and loop of Henle.
      - Excrete sodium, chloride, potassium, water
    - - Prevent kidney failure
      - Reduces pressure in head injury using mannitol and albumin
  - - - Block action of enzyme carbonic anhydrase
      - Excretes sodium, potassium, bicarbonate
    - - Primarily to decrease IOP in patients with open-angle (chronic) glaucoma
  - - - Block action of aldosterone
      - Promote sodium/water excretion and potassium retention
    - - Edema due to heart failure, cirrhosis of the liver