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Vascular Tumors (Pathoma) (Kaposi Sarcoma (Classically seen in (Older…
Vascular Tumors (Pathoma)
Hemangioma
benign tumor comprised of blood vessels
Commonly present at birth
regresses during childhood
often involves skin
can involve liver
skin considerations: possible bleed (
purpura
)
if no purpura: press on it and it would blanch
Angiosarcoma
malignant mesenchymal tumor of endothelial cells
Highly aggressive
Common sites
skin
breast
liver
assd. with exposure to PVC, arsenic, Thorotrast
Kaposi Sarcoma
low grade malignant proliferation of endothelial cells
associated w/ HHV8
Presents as
Purple patches, plaques, nodules on skin
endothelial cells, not complete bv's
pressing on tumor does not blanch since blood is not in vessels
can involve visceral organs
Classically seen in
Older Eastern European males
treat w/ excision
AIDS
can spread early and move to other tissues
Treat w/ ARV so immune sys can kill HHV8 infected cells
Transplant recipients
treat by decrease immumnosuppresives
