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Dementia (beta-amyloid (Aβ) (BACE-1 (the beta-secretase enzyme) (ApoE4),…
Dementia
beta-amyloid (Aβ)
BACE-1 (the beta-secretase enzyme)
ApoE4
Aβ40
Aβ42
amyloid precursor protein(APP)
Disease
Alzheimer's disease (AD) 50-70%
vascular dementia 25%
Lewy body dementia (LBD) 15%
frontotemporal dementia (FTD) Less
Tau
P-Tau
T-Tau
Diagnosis
history of the illness and cognitive testing (Major)
medical imaging and blood tests (Minor)
CSF biomaker
Microglia
neuroinflammation