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20180813蔡宜純醫師 (計畫 (Cell (加入Ang2至細胞 (Apotosis (反加Anti-Ang2), western…

- - - - db mice high level Angpt2
  - - - Apotosis
        
        反加Anti-Ang2
      - western
        
        反加Anti-Ang2
    - - NGS結果找和Apotosis有關的miRNA
      - 114個miRNA 2 fold change
        
        71個up-expression; 43個down
        
        miR33-5p
    - - TargetScan(還要看同源性) & miRMAP
        
        DAVID
        
        TargetScan UUACGU
        
        TargetScan
        
        用Hek293測SOCS5 transfect效能
    - - MICE IHC
      - shSOCS5 看 apotosis
    - - 採集仁和小鼠小便
        
        檢測miR335p表現量和蛋白尿的相關性
- - - - 抑制SOCS5
        
        JAK pathway