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Conformational Analysis (Objectives (Understand the importance of…
Conformational Analysis
What is it?
In chemistry, any of the arrangements of a molecule that result from atoms being rotated about a single bond
Different conformations = CONFORMERS of each other
Revisions
Stereoisomers
Compounds with the same connectivity of atoms but different three dimensional forms/spatial orientations are known as "stereoisomers".
Types
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Configurational Isomers
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Meso-Compounds
A special relationship can occur when molecule has chiral centres but is overall non-chiral. This occurs when there is a symmetry plane within the molecule
Objectives
Understand the importance of conformation in organic chemistry,
Predict and assign the most stable conformation of simple alkanes and cycloalkanes,
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Appreciate the role of strain in determining the reactivity of a molecule,
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