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HIV clinical staging (adults and adolescents clinical staging (clinical…
HIV clinical staging
adults and adolescents clinical staging
clinical stage 2
Moderate unexplained weight loss (<10% of presumed or measured body weight)
Recurrent respiratory tract infections (sinusitis, tonsillitis, otitis media, pharyngitis)
Herpes zoster
Angular cheilitis
Recurrent oral ulceration
Papular pruritic eruption
Fungal nail infections
Seborrhoeic dermatitis
stage 1
asymptomatic, persistent generalized lymphadenopathy
clinical stage 3
Unexplained severe weight loss (>10% of presumed or measured body weight)
Unexplained chronic diarrhoea for longer than 1 month
Unexplained persistent fever (intermittent or constant for longer than 1 month)
Persistent oral candidiasis
Oral hairy leukoplakia
Pulmonary tuberculosis
Severe bacterial infections (such as pneumonia, empyema, pyomyositis, bone or joint infection, meningitis, bacteraemia)
Acute necrotizing ulcerative stomatitis, gingivitis or periodontitis
Unexplained anaemia (<8 g/dl), neutropaenia (<0.5 × 109/L) and/or chronic thrombocytopaenia (<50 × 109/L)
clinical stage 4
HIV wasting syndrome
Pneumocystis (jirovecii) pneumonia
Recurrent severe bacterial pneumonia
Chronic herpes simplex infection (orolabial, genital or anorectal of more than one month in duration or visceral at any site)
Oesophageal candidiasis (or candidiasis of trachea, bronchi or lungs)
Extrapulmonary tuberculosis
Kaposi sarcoma
Cytomegalovirus infection (retinitis or infection of other organs)
Central nervous system toxoplasmosis
HIV encephalopathy
Extrapulmonary cryptococcosis, including meningitis
Disseminated nontuberculous mycobacterial infection
Progressive multifocal leukoencephalopathy
Chronic cryptosporidiosis
Chronic isosporiasis
Disseminated mycosis (extrapulmonary histoplasmosis, coccidioidomycosis)
Lymphoma (cerebral or B-cell non-Hodgkin)
Symptomatic HIV-associated nephropathy or cardiomyopathy
Recurrent septicaemia (including nontyphoidal Salmonella)
Invasive cervical carcinoma
Atypical disseminated leishmaniasis
children clinical staging
clinical stage 1
Asymptomatic
Persistent generalized lymphadenopathy
clinical stage 2
Unexplained persistent hepatosplenomegaly
Recurrent or chronic upper respiratory tract infections (otitis media, otorrhoea, sinusitis, tonsillitis)
Herpes zoster
Lineal gingival erythema
Recurrent oral ulceration
Papular pruritic eruption
Fungal nail infections
Extensive wart virus infection
Extensive molluscum contagiosum
Unexplained persistent parotid enlargement
clinical stage 3
Unexplained moderate malnutritionb not adequately responding to standard therapy
Unexplained persistent diarrhoea (14 days or more)
Unexplained persistent fever (above 37.5°C, intermittent or constant, for longer than one 1 month)
Persistent oral candidiasis (after first six weeks of life)
Oral hairy leukoplakia
Lymph node tuberculosis; pulmonary tuberculosis
Severe recurrent bacterial pneumonia
Acute necrotizing ulcerative gingivitis or periodontitis
Unexplained anaemia (<8 g/dL), neutropaenia (<0.5 × 109/L) or chronic thrombocytopaenia (<50 × 109/L)
clinical stage 4
Unexplained severe wasting, stunting or severe malnutritiond not responding to standard therapy
Pneumocystis (jirovecii) pneumonia
Recurrent severe bacterial infections (such as empyema, pyomyositis, bone or joint infection, meningitis, but excluding pneumonia)
Chronic herpes simplex infection (orolabial or cutaneous of more than 1 month's duration or visceral at any site)
Oesophageal candidiasis (or candidiasis of trachea, bronchi or lungs)
Extrapulmonary tuberculosis
Kaposi sarcoma
Cytomegalovirus infection (retinitis or infection of other organs with onset at age older than one month)
Central nervous system toxoplasmosis (after the neonatal period)
HIV encephalopathy
Extrapulmonary cryptococcosis, including meningitis
Disseminated nontuberculous mycobacterial infection
Progressive multifocal leukoencephalopathy
Chronic cryptosporidiosis (with diarrhoea)
Chronic isosporiasis
Disseminated endemic mycosis (extrapulmonary histoplasmosis, coccidioidomycosis, penicilliosis)
Cerebral or B-cell non-Hodgkin lymphoma HIV-associated nephropathy or cardiomyopathy
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