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GIT (OESOPHAGUS (INFLAMMATORY (Corrosive Injury (Pills that adhere to…

- - - - Commonest cause of oesophagitis
      - Strat. squamous of esophagus is resistant to abrasion by food but sensitive to acid
    - - Pills that adhere to esophageal lining
      - Complications: Haemorrhage /Stricture
      - Alcohol,Acids, Alkali
      - Stratified squamous mucosa damaged by irritants
    - - Common in immunosuppressed
      - Herpes simplex virus, Cytomegavirus &Candida common
  - - - Diseases that obstruct portal blood flow cause portal HPT
      - This leads to development of varices
      - Drugs & other materials absorbed in intestines are processed in liver before entering systemic circulation (First Pass Effect)
      - Venous blood goes to liver before entering IVC.
      - Which are abnormal, enlarged veins
      - Can lead to massive & life threatening bleeding
      - Bleeding occurs because of low clotting factors, platelets and difficulty to close ruptured vessel.
      - Common cause is Alcohol Liver Disease
    - - Longitudinal linear lacerations at gastroesophageal junction
      - Induced by vomiting
  - - - Separation of crura & protrusion of stomach into thorax resulting in a gap.
  - - - Radiology Features
      - Desmoplasia
      - Anatomy
        
        serosal surface adjacent to major structures
        
        mucosal lymphatics
        
        Travels up & down length of esophagus
        
        Which empty into intramuscular lymphatics
        
        Empty into submucosal lymphatics
- - - - Poor circulation
      - Injury to mucosal barrier
    - - Autoimmune
      - Chemical
      - Helibacter Pylori