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TPN (Daily req. (Water 30ml/kg, Calories 30kcal/kg, Na 2mmol/kg, K…

- - - - Resp failure - muscle weakness
      - Cardiomyopathy, hypotension, arrhythmia
      - Neurological - confusion, seizures
      - ATN
      - Skeletal - rhabdo, weakness
      - Endocrine - insulin resistance
      - Haematological - WC dysfunction, thrombocytopenia, immune fx, sepsis
- - - - RBC (no mitochondria) depend on glucose
      - Brain metabolism also depends on glucose
  - - - Immune dysfunction
      - Reduced oxygenation
      - Fatty liver
      - Platelet aggregation