Please enable JavaScript.

Coggle requires JavaScript to display documents.

L4/5 Drug Actions (I & II) Pharmacodynamics Drug action is dose…

- - - - Actinomycin D on DNA
      - Sterptomycin on RNA
    - - Fluoxetine on Serotonin
      - D-Tubocurarine on Nicotine Receptor
      - Penicillin on Transpeptidase
        
        Bacterial cell wall synthesis
  - - - Non-competitive
        
        Irreversible
        
        Reversible
      - Competitive
        
        Analogy: Musical chairs with 2 teams; Numbers win
        
        Log Curve: Parallel shift to right
        
        Irreversible
        
        Reversible
  - - - Receptor Potency
        
        Dose required to produce a given degree of response
        
        Only relevant when the receptors are SIMILIAR
      - Clinical Potency
        
        Dose required to produce a given degree of response
        
        Largely dependent on pharmokinetic factors
        
        Such as Absorption / Metabolism / First Pass / Elimination