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Kidney Drugs (ACE Inhibitors ( Capt, Enal, Lisin, Rami-OPRIL) (Inhibited…
Kidney Drugs
ACE Inhibitors ( Capt, Enal, Lisin, Rami-OPRIL)
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ACE= Aldosterone, ADH, (Pit gland) + Vasoconstriction
Loop Diuretic
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Blocks Na/Cl/K cotransporter, all excreted more
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K+ sparing diuretic- CD
Spironolactone: Inhibits Aldosterone (Acting on K/Na ATPase) by blocking mineralocorticoid receptor. prodrug
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Thiazide- Like- DCT
Chlortalidone: Binds thiazide sensitive Na/Cl cotransporter, increasing K+ excretion indirectly.
Indapamide: blocks the delayed rectifier potassium current (IKs) without altering the rapid component (IKr) or the inward rectifier current
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Thiazides- DCT
Bendroflumethiazide
Inhibits Na/Cl blocking Cl reabsorption. Increasing Na, Cl, H2O excretion
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