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Breast Cancer Management (Inoperable (Visceral Metastasis, Large lesion in…
Breast Cancer Management
Operable
4/more LNs
Large breast w/ large lesion
Inoperable
Visceral Metastasis
Large lesion in small breast
N3 (Supraclavicular)
T4 (Cut through tumour is bad idea)
Rx primary chemotherapy/ neoadjuvant
Anatomical Stage
Early Breast Cancer
Primary Surgery
Locally Advanced Breast Cancer
Neoadjuvant Chemotherapy (downstage)
Metastatic
Palliative
Non-Luminal Cancer
Neoadjuvant
Assess Rx Response
Partial Response [Swiss Cheese effect]
Complete Pathological Response [lesion disappears]
Stable [No response]
Concentric Decrease in Size [diameter decreases]
Unresponsive [Grow]
Prognostic Marker
Surrogate Marker for testing the Efficacy of Rx
Same outcome as Adjuvant Therapy
Assist oncologist to tailor treatment
Hormone Receptor Negative