Please enable JavaScript.

Coggle requires JavaScript to display documents.

Pulmonary Fibrosis (Risk factors (injury (Symptoms (Screenings (Lung…

- - - - inflammatory mediators and initiation of an anti-fibrinolytic coagulation cascade
        
        Plugs the damaged vessels w/ platelet & fibrin rich clot
        
        Platelet recruitment progresses into vasodilation with increased permeability - increased leukocytes to the area
        
        Neutrophils and lymphocytes to the area w/ macrophages to clear the area
        
        Inflammatory cytokines and growth factors
        
        IL-1 & LPA
        
        TGF beta
        CTGF
        IGF-1
        
        Imbalance of cytokines/growth factors leads to surplus of myofibroblast production
        
        1 more item...
    - - Moldy crop: straw, corn, silage, grain and animal byproducts
        
        Contain the spores of special, heat-tolerating bacteria
        
        Two types of bacteria: Micropolyspora faeni and Thermoactinomyces vulgaris
        
        Inhale a large amount of dust and spores from moldy hay
        
        Immune system produces antibodies to attack antigens (bacteria)
        
        Trigger allergic reaction by further exposure
        
        White blood cells move into the lungs to attack the antigens
        
        1 more item...
        
        Farmer's Lung Disease
        
        What to look for
        
        elevated WBC count
        
        Fever
        
        SOB
        
        Tightness in chest
        
        Acutely: tachycardia/tachypenia
      - Tobacco
    - - Dry, hacking cough
      - Fast, shallow breaths
      - Loss of appetite and Gradual unintended weight loss
      - Rapid heart rate
      - Aching joints and muscles
      - Clubbing of fingers and toes
      - Screenings
        
        CT Scan
        
        Chest X-ray: normal
        
        Echocardiogram
        
        Lung function
        
        Pulmonary Function Test
        
        Exercise stress test
        
        Arterial blood gas test
        
        Medications
        
        pirfenidone (Esbriet) and nintedanib (Ofev)-**
        
        Glucocorticoids
        
        Anti-acids for acid reflux
        
        Cough medication
        
        Treatment Methods
        
        Pulmonary therapy
        
        Oxygen Therapy
        
        Lung Transplant
        
        lung allergy challenge test
        
        lung biopsy
        
        Blood test for antibodies
      - a sudden general feeling of sickness