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TIMELESS neuroimaging for randomization (To determine type of occlusion…
TIMELESS neuroimaging for randomization
To determine type of occlusion
MRA or CTA
adequate? (YES/NO)
YES
what to measure?
Patients screened with MRA: intracranial MRA; cervical MRA is not required
Patients screened with CTA: only intracranial CTA is required
NO
what to use?
Tmax > 6s perfusion defict
target mismatch profile
To measure ischemic core volume, mismatch ratio, and mismatch volume
CTP or MRI
Both are available? (YES/NO)
YES
: use MRI results
What to measure?
ischemic core lesion volume
Tmax > 6s lesion volume
NO
: One is available? (YES/NO)
YES
: use available one
What to measure?
ischemic core lesion volume
Tmax > 6s lesion volume
NO
exclude: not eligible for study randomization