typically mild but becomes more pronounced over time
Acute infection: decr in Hb levels of 2–3 g/dL within 1 or 2 d; largely related to hemolysis of RBCs near end of their natural life span; fever and cytokines released exert a selective pressure against cells w/ more limited capacity to maintain RBC membrane
In most, the mild anemia well tolerated & symptoms, if present, a. w/ underlying disease
Occasionally, in preexisting cardiac disease, moderate anemia (hemoglobin 10–11 g/dL) may be a. w/ angina, exercise intolerance, and shortness of breath
Table 126-6.