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CHAPTER 8 INSTRUMENTATION AND CONTROL (CONTROL (control loop (PID…
CHAPTER 8
INSTRUMENTATION AND CONTROL
more knowledge is in Process Control
CONTROL
definition
of WHAT conditions
manual
automatic
HOW
sensors
penetrate into the interior (of the fermentor)
dissolved-oxygen sensors
for measurement
equation :red_flag:
pO2: partial oxygen xxx?
Ex: digital, optical oxygen sensor = NEW PRODUCT :red_flag:
fluorescence :red_flag:
for control
pH sensors
2 electrodes :red_flag:
sensing
reference
one based on
activity
definition of
pH
others based on different systems
sensitive to ions or protons :question:
dissolved CO2 sensor
CO2 + H2O
analysis of inlets and outlets :!!: (learn it carefully)
CO2 in gas phase
infrared CO2 analyser
Redox potential
in liquid phase (b/c they need solvents for carring out the redox reactions?)
microbial biomass
turbidity
but some limits when the solutions are too dark that do not let the light pass
real-time estimation: very difficult
BUT how about Tecan :question:
https://www.tecan.com/
indirect methods
operates on the samples
operates in labs
on-line vs. in-line (the best) vs. off-line
note: black wires are part of the off-line systems.
control loop
one example in SL 12 :!:
PID controller
offset (notice the dotted line)
P: proportion
I: integral
D: slope
variables
(and related functions) are chemical or physical properties
but can be
more than ONE
possible function
.
foam control
antifoam
COMPUTER APPLICATIONS IN FERMENTATION
statistical analysis :fire: