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TINIDAZOLE (CAUTION/PRECAUTION (Pragnancy (2nd & 3rd trimester)…

- - - - In Vivo studie (on male rat)
        
        Spermatogenic effects resulted from 300 and 600 mg/kg/day dose levels.
        
        reduced fertility
- - - - Placenta
      - BBB
      - Breast milk
  - - - Oxidation
      - Hydroxylation
      - Conjugation
- - - - Single 2 g dose
    - - 50 mg/kg (up to 2 g)
  - - - 2 g dose per day for 3 days
    - - 50 mg/kg/d (up to 2 g/d)
  - - - 2 g oral dose once daily (for 2 days)
      - 1 g oral dose once daily (for 5 days)