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CARDIOVASCULAR SYSTEM (HEART (Conduction system (AV node (Delay signal…
CARDIOVASCULAR SYSTEM
HEART
-
Heart valves
-
Function
- Open: allow blood flow
- Close: prevent to backflow of blood
- 2 atrioventricular valves: prevent backflow of blood into atria during contraction of ventricles.
- 2 semilunar valves: prevent backflow of blood from great arteries into ventricles.
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Conduction system
AV node
- Delay signal while ventricles fill with blood
AV bundle
- Bundle of His
- Connects atria to ventricle
Bundle branches
- Conduct impulses through interventricular septum
Purkinje fibers
- Stimulates contractile cells of both ventricles
SA - sinoatrial node
- "Pace maker"
- In right atrium
- Generate electrical signal
- Atria contract - using gap junction to spread signal
- Signal to AV node
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BLOOD VESSELS
Capillary
Fenestrated
- "Window" - pores
- More leaky
- High rates of exchange
- Small intestine, kidney, choroid plexus, endocrine glands.
Sinusoid
- Large, winding
- Exchanges things large: proteins, whole cells
- Liver, red bone marrow, spleen
Continuous
- Most common
- CNS, lungs, skin, skeletal muscle, smooth muscle
- Least - leaky
Vein
Medium-sized vein
- Lower blood pressure
- Fewer elastic fibers than artery
Venule
- Much like capillaries
- Some exchange
- 1-2 layers of smooth muscle
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Artery
Definition
- Vessel carry blood away from heart
Types
-
Arterioles
- 1-2 layers of smooth muscle.
- Changing diameter to regulate blood flow
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BLOOD
Proteins
Globulin
- Antibodies - protect us from pathogens
- Transporters
Fibrinogen
- Involved in blood clotting
Albumin
- Keep water in blood vessels
Plasma
- Liquid - 90% water
- Irons, sugar, hormones, vitamins, amimo acids, lipids.
- More than 100 different molecules
Cells
-
Leukocyte
- Neutrophil
- Eosinophil
- Basophil
- Lymphocyte
- Monocyte
Erythrocyte
- Bags of hemoglobin - binds O2 & contains iron
- Created in red bone marrow
- Transport oxygen
Platelets
- Pieces cytoplasma of a larger cell - megakaryocyte
- Stop bleeding + clot information