Validity of Diagnosis of Schizophrenia

Comorbidity

Culture Bias

Gender Bias

Symptom Overlap

Definition

Research

Evaluation

One or more additional disorders/diseases occur simultaneously

Can create problems w/ reliability of diagnosis b/c confusion over which disorder is being diagnosed

Schizophrenics often suffer from depression as well

issues of descriptive validity

having simultaneous disorders suggests that schizophrenia is not separate disorder

Sim et al.

32% of 142 hospitalised schizophrenics had additional mental disorder

Co-morbidity creates problems in achieving valid diagnosis of schizophrenia

Goldman

50% of schizophrenics had a co-morbid medical condition (substance abuse/polydipasia)

Reliable + valid diagnosis of schizophrenia problematic

Buckley et al.

50% o schizophrenics had co-morbid depression

15% co-morbid panic disorder

29% PTSD

23% OCD

Jeste et al.

schizophrenics w/ co-morbid conditions excluded from research but form majority of patients

suggest research into causes cannot be generalised to most sufferers

knock on effect to what treatment such patients should receive

High levels of certain co-morbid disorders --> some argue such co-morbidities = separate sub-types of disorder

problem = differing schizophrenia from bipolar disorders

Schizophrenia related changes in mood often include mania + depression

sometimes don't meet criteria to be diagnosed as separate disorders

schizophrenics often substance abuse (alcohol, cannabis)

Definition

Tendency to over-diagnose members of other cultures w/ schizophrenia

People of Afro-Caribbean descent in Britain are much more likely than white people to be diagnosed as schizophrenic

More likely to be confined in hospitals

Psychologists are racist b/c see black schizophrenics as more dangerous?

Heightened stress levels people from ethnic minorities experience contribute to higher levels of schizophrenia

Research

Cochrane

Incidence of schizophrenia in the West Indies + Britain similar = 1%

BUT people of Afro-Caribbean origin are 7x more likely to b diagnosed w/ schizophrenia when living in Britain

either suggests that AC ppl in Britain have more stressors or that invalid diagnoses made b/c cultural bias

McGovern & Cope

2/3 of patients detained in Birmingham hospitals were first/second generation Afro-Caribbeans

1/3 = white/asian

cultural bias to over-diagnose schizophrenia in black population

Ineichen

32/89 confinements in "closed" wards in Bristol hospitals were of non-white patients

Bigger proportion of non-whites in society

tendency to see non-white schizophrenics as more dangerous

Whaley

main reason for incidence of schizophrenia among black Americans (2.1%) greater than white (1.4%) cultural bias

Differences in symptom expression overlooked by practitioners

Lack of validity in diagnosing schizophrenia cross culturally

Evaluation

Fernando says higher levels of schizophrenia in minorities b/c triggered by greater levels of poverty and racism

Cochrane pointed out that only ethnic minority to experiences this is Afro Caribbean

may be because afro-caribbeans have little immunity to flu and child born to mother who had flu while pregnant are 88% more likely to get schizophrenia

Rack

In many cultures normal to see and hear deceased loved ones as part of grieving process

People exhibiting this behaviour in Western culture are liable to be diagnosed as schizophrenic

Cochrane and Shashidharan

racism and social deprivation immigrants suffer negatively affect mental health

Clinicians wrongly attribute their behaviour to their ethnicity.

Definition

Disagreement between psychologists over the gender prevalence rate of schizophrenia

Accepted belief was males and female equally vulnerable to the disorder

BUT some argue that clinicians, majority men, misapply diagnostic criteria to women

Recent studies have shown there are more than 50% more male sufferers

When making diagnosis, clinicians often fail to consider males tend to suffer more negative symptoms than females

also higher levels of substance abuse in men

Women have better recovery rates and lower relapse rates

Clinicians tend to ignore fact that there are different predisposing factors between males and females

Giver them different vulnerability levels at different points of life

Difference sin classification of schizophrenia

first onset occurring earlier in males (18-25 years)

Females generally 4-10 years later

two peaks for male schizophrenia (21 and 39)

three peaks for females (22, 37, 67 years)

Research

Lewin et al.

Reichler-Rossler + Hafner

if clearer diagnostic criteria applied, number of female sufferers became lower

gender bias in original diagnosis

Supported by Castle et al.

Found using more restrictive diagnostic criteria that the male incidence was more than twice of that of females

males have more severe negative symptoms

Reinforced by Galderisi et al.

found that males scored higher for negative symptoms

Hambrecht and Hafner

Male sufferers had higher levels of substance abuse

Haro et al.

Relapse rates higher in males but recovery higher in females

ALL suggest gender bias in clinicians not considering such important factors when making diagnosis

Kulkarni et al.

female sex hormone estradiol effective in treating schizophrenia when added to antipsychotic therapy

suggests may be different protective and predisposing factors in male and female vulnerability to schizophrenia

Clinicians do not consider this

Evaluation

Females tend to first develop schizophrenia between four and ten years later than men

Women can develop much later form of post-menopausal schizophrenia

Difference between types of schizophrenia between males and females

ALL question validity of diagnosis

Research findings indicate there is a case to be made for different diagnostic considerations for males and females

cast doubts on validity of schizophrenia as separate disorder

Difference in age where males and females experience schizophrenia may be related to different types of stressors both sexes experiences at different ages

AND age-related variations in female menstrual cycles

Definition

In diagnosing schizophrenia, symptoms of disorder are also found in other disorders

Makes deciding which particular disorder someone is suffering from difficult for clinicians

Occurs especially with bipolar disorder

Depression + hallucinations is a common symptom

can also occur w/ autism and cocaine intoxication

Research

Serper et al.

assessed patients w/ comorbid schizophrenia + cocaine abuse (schizophrenics + abusers on their own as well)

Although overlap, possible to make accurate diagnoses

Konstantareas and Hewitt

compared 14 autistic patients w/ 14 schizophrenics

none of schizophrenics had symptoms of autism but 7 autistics had symptoms of schizophrenia

some support for idea of symptom overlap

Ophoff et al.

assessed genetic material in 50,000 pps

foundof seven gene locations of the genome associated w/ schizophrenia, 3 also associated w/ bipolar

genetic overlap between the two disorders

Evaluation

genetic overlap between mental disorders suggests gene therapies might be developed that simultaneously treat both disorders

recently developed method of ascertaining which particular disorder someone is suffering w/ is to examine grey matter content of brain

schizophrenics experiences decrease of grey matter but bipolar sufferers cannot

Ketter reports that misdiagnosis due to symptom overlap can lead to years of delay in receiving relevant treatment

In that time suffering and further degeneration occur as well as high levels of suicide

Makes valid diagnosis difficult to achieve

Less compliant w/ medication

treating disorder more difficult