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NS 34 - Limbic System + Hypothalamus (ii) (Wernicke-Korsakoff Syndrome…
NS 34 - Limbic System + Hypothalamus (ii)
Fimbria
efferents from hippocampus to fornix
Septal Nuclei/Area
when stimulated - orgasm
when ablated - uncontrollable rage
Papez's circuit
outdated
controls emotional expression
learning
repetition, habituation
reward centres: septal nuclei, nucleus accumbens, olfactory regions, brainstem
punishment centres: PAG, thal, amygdala, hippocampus
Wernicke-Korsakoff Syndrome
in alcoholics
thiamine deficiency
capill haemorrhages in upper brainstem + limbic system
acute or gradual
Wernicke encephalopathy
confusion, ocular signs, ataxia
reversible
Korsakoff psychosis
recovery possible, but with irreversible memory loss + inability to form new memories