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Acute liver failure (Aetiology (Metabolic Wilson's disease …

- - - - Dietary support
        Indication: malnourished, ALD
        E.g. thiamine anf folate (pabrinex)
      - Mannitol
        Indication: encephalopathy
        E.g. IV 20% mannitol
        MOA: reduces cerebral oedema
      - Correct bleeding deficits
        E.g. vit K, FFP, platelets
      - Abx
        Indication: suspected infection
      - Lactulose
        Indication: encephalopathy
        MOA: reduces nitrogen-forming gut bacteria,
        reduces ammonia formation and encephalopathy